Strain-specific variations in cation content and transport in mouse erythrocytes
نویسندگان
چکیده
منابع مشابه
Strain-specific variations in cation content and transport in mouse erythrocytes.
Studies of ion transport pathophysiology in hematological disorders and tests of possible new therapeutic agents for these disorders have been carried out in various mouse models because of close functional similarities between mouse and human red cells. We have explored strain-specific differences in erythrocyte membrane physiology in 10 inbred mouse strains by determining erythrocyte contents...
متن کاملThe connexion between active cation transport and metabolism in erythrocytes.
1. A study has been made of the dependence on the concentrations of internal Na(+) and external K(+) of lactate and phosphate production in human erythrocytes. 2. Lactate production was stimulated by Na(+) and K(+) but only when they were internal and external respectively. The stimulation was counteracted by ouabain. The production of phosphate was affected in the same way. 3. There is a quant...
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In the present studies we have explored the relation between ouabain binding and the inhibition of potassium influx in intact human erythrocytes. The rate at which bound ouabain molecules dissociate from the erythrocyte membrane is not altered by complete replacement of choline with sodium or by partial replacement with potassium. These findings indicate that the effects of these cations on oua...
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15 صفحه اولphylogeography and genetic diversity of the lesser mouse- eared bat (myotis blythii) in iran
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ژورنال
عنوان ژورنال: Physiological Genomics
سال: 2013
ISSN: 1094-8341,1531-2267
DOI: 10.1152/physiolgenomics.00143.2012